Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Non-Neoplastic Biopsies by Arnold Christina & Lam-Himlin Dora & Montgomery Elizabeth A

Author:Arnold, Christina & Lam-Himlin, Dora & Montgomery, Elizabeth A.
Language: eng
Format: epub
ISBN: 978-1-4963-0099-7
Publisher: LWW
Published: 2014-10-22T16:00:00+00:00

Figure 3.160 Malabsorption pattern, abnormal crypt to villous ratio. This biopsy from the second portion of the duodenum has a crypt depth to villous height ratio of approximately 1:1 which is the result of both crypt hyperplasia and villous blunting. Normal crypt to villous ratios range from 1:3 to 1:5. Compare this figure to Figure 3.3, which has a normal crypt to villous ratio. Care should be taken not to overcall villous blunting in the bulb, as villi in the bulb are naturally shorter.

The severity of features, whether manifested singly or in combination, can serve as diagnostic clues; however the features are nonspecific, and they may be seen in an ever-increasing list of conditions that require clinical correlation, as discussed below.

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